Types of biosensors in contact lenses.
Introduction: The rapid advancement of technology has enabled the realization of personalized medicine. According to the global demographics of health reported by the World Health Organization, 75% of the world population is defined as sub-health, but only 20% needed to be hospitalized. As the sub-health population has become more concerned about their quality of life, the demand for so-called point-of-care (POC) diagnostics is rising. tear fluid contains relatively rich proteins that have been identified and share similar constituents to that of blood. This similarity is attributed to the plasma leakage across the blood-tear barrier and thus enables the development of biosensors that specifically target analytes within the tear fluid. Although blood testing remains second to none in the standard liquid biopsy, tear fluid can be collected in a non-invasive way. This feature makes tear fluid a promising sample in some preliminary clinical tests. Followed by this concept, contact...